These decks attack The EPIC Storm a little differently, they attempt to lower your life-total very quickly to shut off Ad Nauseam while having very little disruption otherwise. If this is the case, don't use your life-total as your resource!
The biggest piece of advice I can give for these decks is to mulligan aggressively (especially under the London Mulligan). There's little need to keep a bad or clunky seven-card hand when you can simply keep a better six or five card hand that can kill our opponent before turn three. It actually works to our advantage, but also aligns well with one of our game-plans in Echo of Eons. Which will rebuild our initial hand, it's like starting the game fresh except for the fact that you'll have a few permanents and hopefully some mana floating!
What is effective in this matchup?
Against these decks, I typically prefer to cast Empty the Warrens from a high life total very quickly. This should prevent you from dying to burn cards, Goblin Chainwhirler, or too many blockers allowing the opponent to stabilize. If you're unable to do this, I would lean on Echo of Eons. Unlike the blue match-ups, you don't need to protect yourself via Defense Grid here as your opponent is extremely unlikely to have any sort of meaningful interaction in hand. The risk of drawing a bad seven card hand is why I prefer to Empty the Warrens if possible, as I believe Empty the Warrens tends to be more of a sure-thing against these decks. I wouldn't risk an Ad Nauseam after turn one due to cards like Fireblast (Burn and sometimes Zoo). Of these three decks, I've found Ad Nauseam to be the best engine against Goblins as they rarely have instant speed damage or interaction in general.
Against all three, Duress is lacking — while Duress has targets in each matchup, it's not exactly what you want to be spending your resources on as the cards that matter most are all creatures. The two most common and important creatures against these decks are Eidolon of the Great Revel and Thalia, Guardian of Thraben. Both of these are very difficult to win through after they've resolved, which means that you should aim to combo before they can land or keep a hand with Thoughtseize (at least in game one).
These decks traditionally attempt to fight back versus Combo decks by using permanent-based disruption, be ready for it! Have your copies of Chain of Vapor, Echoing Truth, and Crash ready!
Against Burn, you're really just looking to answer Eidolon of the Great Revel and Pyrostatic Pillar. I have seen things such as Mindbreak Trap and Volcanic Fallout of the sideboard of the basic Mountain deck, so keep this in mind if you're presented the option on casting a discard spell or not during the combo turn. Speaking of discard spells, due to the life-loss of Thoughtseize, we tend to shave a few copies during sideboarding against the deck looking to burn our house down.
It's not shocking, but against all three decks you should be siding out Defense Grid. Don't worry about losing an artifact for Metalcraft as it's not as relevant as a dead card in your hand for these match-ups.
For Goblins, I would easily take out Duress as it has very few targets it can actually hit in the archetype opting to play over twenty-five creatures. I would be preparing for artifacts post-board against the "little-red men" in their attempt to prove they're the better Goblin deck (Spoiler: they're not), these artifacts are likely Chalice of the Void and Thorn of Amethyst. While we are the better Goblin deck, I've actually found Empty the Warrens to be fairly unreliable against Goblins since the printing of Goblin Chainwhirler, while they don't play too many copies, there's no need to risk losing to this card. Because of this, I often sideboard out my Goblin generator.
Humans and Zoo tend to play out fairly similar for The EPIC Storm despite the decks being very different, you're simply looking to combo-off before Thalia, Guardian of Thraben, Gaddock Teeg, Ethersworn Canonist, and other disruptive friends hit the table. Keep in your mind that Humans tends to play one or two main-deck sweepers for Goblin Tokens and additional answers post-board. I put a real sense of mulliganing aggressively in these match-ups.
Important Cards in the Match-up